- 中图分类号: Q3
- 语种: ENG
- 出版信息: Academic Press_RM 2015 484页
- EISBN: 9780128004715
- PISBN-P: 9780127999586
- 原文访问地址:
KG评星
知识图谱评星,是一种基于用户使用的评价体系,综合图书的评论数量、引文数量、Amazon评分以及图谱网络中节点的PageRank值(即考虑相邻节点数量和重要性)等多种因素计算而得出的评价数值。星级越高,推荐值越高。CAT核心级
核心学术资源(CAR)项目作为教图公司推出的一项知识型服务,旨在打造一套科学、有效的图书评价体系,并协助用户制定相应的馆藏建设方案。CAR项目调查和分析12所世界一流大学的藏书数据,以收藏学校的数量确定书目的核心级,核心级越高,代表书目的馆藏价值越高。选取核心级在三级以上,即三校以上共藏的图书作为核心书目(CAT)。Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapiesHelps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspringChapters are replete with clinical examples to empower the basic biology with translational significanceOffers more than 100 illustrations to distill key concepts and decipher complex science